Wednesday May 13, 2009


Extrapontine myelinolysis from severe hyponatremia

(a) Normal MRI scan taken five months before the episode of severe hyponatremia, when serum sodium was 140 mmol/l.

(b) Ten days after the episode of severe hyponatremia, MRI scan showed bilateral high-intensity abnormalities in the lenticular nuclei and in the head of the caudate nucleus (arrows).

(c) At day 32, the lesions shown in panel b appear more pronounced (arrows).

(d) At day 32 with fluid-attenuation inversion recovery, high intensity lesions were also observed in the precentral gyrus (arrows).



Reference: Click to get article

Severe hyponatremia followed by extrapontine myelinolysis - Kidney International (2006) 69, 423.